To this end, the ability of rotaviruses to exchange genetic material between human and animal viruses during co-infection results in the generation of novel viruses.īy using various surveillance and diagnostic methods and techniques, the estimations state that rotavirus infections cause around half of all gastroenteritis in children less than five years of age. Interspecies transmission plays a crucial role in the diversity of rotaviruses. One of the major challenges in epidemiological studies is the rapid evolution of rotaviruses via different mechanisms. Therefore, a major emphasis has been put on the development of a safe and effective vaccine for use in early infancy. Additionally, these viruses are responsible for over 500,000 visits to a medical practitioner annually in the United States alone. Rotaviruses are thought to cause more than 800,000 deaths annually in children aged less than 5 years in developing countries. Image Credit: Kateryna Kon / Introduction The infection caused by these agents is common in both tropical and temperate climatic areas and shows distinct seasonality. Rotaviruses are non-enveloped viruses of the family Reoviridae and a major cause of severe dehydrating diarrhea both in developed and developing countries.
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